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Continuing Education in Anaesthesia Critical Care and Pain | Volume 4 Number 1 | 2004
© The Board of Management and Trustees of the British Journal of Anaesthesia 2004

Management of the critically ill child with sepsis

Stephen Playfor, MBBS DCH MRCP MRCPCH MD, Consultant Paediatric Intensivist
Royal Manchester Children's Hospital, Hospital Road, Pendlebury, Manchester M27 4HA
Tel: 0161 727 2978, Fax: 0161 727 2198, E-mail: stephen.playfor{at}cmmc.nhs.uk

Sepsis is broadly understood to be the systemic response to infection. It can be said to exist when an infectious process has triggered the systemic inflammatory response syndrome (SIRS). The term ‘SIRS’ was coined in 1992 by the American College of Chest Physicians and Society of Critical Care Medicine to describe the non-specific inflammatory process occurring in adults after trauma, infection, burns, pancreatitis and other diseases.


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