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Continuing Education in Anaesthesia, Critical Care & Pain 2004 4(4):111-113; doi:10.1093/bjaceaccp/mkh035
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Continuing Education in Anaesthesia, Critical Care & Pain | Volume 4 Number 4 2004 © The Board of Management and Trustees of the British Journal of Anaesthesia 2004

Anaphylaxis

Sally-Ann Ryder, BSc MB BS MRCP FRCA, Specialist Registrar in Anaesthesia
The Royal Berkshire Hospital NHS Trust, London Road, Reading, RG1 5AN

Carl Waldmann, MA MB BChir FRCA EDICM, Consultant in Anaesthesia and Intensive Care
The Royal Berkshire Hospital NHS Trust, London Road, Reading, RG1 5AN
Tel: 01189 877065, Fax: 0118 9 877067, E-mail: cswald{at}aol.com (for correspondence)

Owing to the nature of their work, anaesthetists are involved in adverse drug reactions more commonly than most other clinicians. These adverse reactions to drugs can be classified as predictable or unpredictable. Predictable reactions are usually dose dependent, reproducible, and are often accepted as expected side-effects of the drug (e.g. hypotension after injection of thiopental). Unpredictable drug reactions may be classified as anaphylactoid or anaphylactic, and are dose independent.


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M. E. McBrien, S. T. Webb, D. S. Breslin, A. D. Axon, and J. M. Hunter
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Br. J. Anaesth., April 1, 2005; 94(4): 547 - 548.
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