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Continuing Education in Anaesthesia, Critical Care & Pain Advance Access originally published online on August 22, 2005
Continuing Education in Anaesthesia, Critical Care & Pain 2005 5(5):171-174; doi:10.1093/bjaceaccp/mki045
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Continuing Education in Anaesthesia, Critical Care & Pain | Volume 5 Number 5 2005 © The Board of Management and Trustees of the British Journal of Anaesthesia [2005]. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Congenital diaphragmatic hernia in the neonate

Hannah King, MB ChB FRCA, Research Fellow in Paediatric Anaesthesia
University of Liverpool, (Honorary) Consultant Paediatric Anaesthetist, Royal Liverpool Children's Hospital, Eaton Road, Liverpool, L12 2AP

Peter D Booker, MBBS FRCA MD, Senior Lecturer in Paediatric Anaesthesia
University of Liverpool, (Honorary) Consultant Paediatric Anaesthetist, Royal Liverpool Children's Hospital, Eaton Road, Liverpool, L12 2AP
Tel: 01512 525223, Fax: 01512 525460, Email: peterdb{at}liv.ac.uk (for correspondence)

The prevalence of congenital diaphragmatic hernia (CDH) ranges between 1:2000 and 1:4000 live births; it accounts for 8% of all major congenital anomalies. Recurrence risk for a subsequent pregnancy is estimated at 2%.1 Approximately 90% of diaphragmatic defects occur posterolaterally and 80% are left-sided. The severity of the condition varies widely, the degree of pulmonary hypoplasia and pulmonary hypertension largely determining outcome. After recent advances in the care of these patients, several centres are now reporting survival rates >80%. This improved survival is ascribed to increased knowledge of the pathophysiology of the condition and, consequently, better perioperative management.


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