Continuing Education in Anaesthesia, Critical Care & Pain | Volume 6 Number 1 2006 © The Board of Management and Trustees of the British Journal of Anaesthesia [2006]. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Anaesthesia and cognitive disturbance in the elderly
Department of Anaesthesia, Royal Manchester Children's Hospital, Hospital Road, Pendlebury, Manchester M27 4HA
Department of Anaesthesia, Royal Lancaster Infirmary, Ashton Road, Lancaster LA1 4RP
Tel: 01524 583528 Fax: 01524 583519 E-mail: asevern@ageanaesthesia.demon.co.uk (for correspondence)
| The first 150 words of the full text of this article appear below. |
| Key points Perioperative delirium and longer term cognitive disturbance are common and disabling consequences of anaesthesia and surgery in the elderly. Evidence is emerging that the risk of postoperative delirium can be predicted by preoperative screening of otherwise asymptomatic patients.
The risk of prolonged postoperative cognitive dysfunction (POCD) is Regional anaesthesia reduces the risk of cognitive impairment in the immediate postoperative period but appears to have no effect on the incidence of prolonged POCD. The risks of cognitive decline should always be considered and discussed when major surgery is contemplated in elderly patients.
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Decline in cognitive functioning after surgery, particularly in the elderly, has been anecdotally appreciated by the profession and
| Delirium |
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| Dementia |
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Anaesthetic assessment
| Postoperative cognitive dysfunction |
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Possible causes of POCD
Emboli
Perioperative physiological disturbances
Pre-existing cognitive impairment
Other factors
| Anaesthetic technique and postoperative cognitive impairment |
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Premedication
Conduct of anaesthesia
| Future developments |
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10% following major surgery in patients of more than 60 yr of age. Increasing age is a risk factor and the incidence in patients of more than 80 yr of age may be as high as one in three.