Continuing Education in Anaesthesia, Critical Care & Pain | Volume 6 Number 1 2006 © The Board of Management and Trustees of the British Journal of Anaesthesia [2006]. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Multiple Choice Answers
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- 1. Concerning the skeletal muscle sarcolemmal membrane potential:
(a) True; (b) False; (c) False; (d) False; (e) True
(a) Nernst equation. (b) The Nernst potential is not reached because of inactivation of Na+ channels and activation of K+ channels. (c) Cl currents contribute to resting membrane potential. (d) Unlike cardiac muscle, there is no plateau potential. (e) Is true.
- 2. Excitation-contraction coupling in skeletal muscle:
(a) False; (b) False; (c) True; (d) False; (e) False
(a) Unlike cardiac muscle. (b) The SERCA pump removes Ca2+ from the cytoplasm. (d) The opposite is trueexcitationcontraction coupling overcomes Mg2+ inhibition of the ryanodine receptor. (e) If anything, the opposite is true.
- 3. Concerning skeletal muscle proteins:
(a) True; (b) False; (c) True; (d) False; (e) False
(a) Actin is present in thin filaments and in cytoskeletal elements. (b) Titin is the largest. (d) Titin is associated with thick filaments. (e) Nebulin is associated. . . [Full Text of this Article] - 2. Excitation-contraction coupling in skeletal muscle: