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Continuing Education in Anaesthesia, Critical Care & Pain 2007 7(5):177-178; doi:10.1093/bjaceaccp/mkm034
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© The Board of Management and Trustees of the British Journal of Anaesthesia [2007]. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

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Gordon Drummond of Edinburgh contacted us regarding the article on ‘Pharmacokinetics and Anaesthesia’ by Fred Roberts and Dan Freshwater-Turner (CEACCP 2007; 7(1): 25–29). He was unhappy with the assertion that ‘an inhaled drug...crosses the alveolar membrane into the blood along its partial pressure gradient. This produces an exponential wash-in...’. Dr Drummond writes that ‘This suggests that the exponential wash-in is caused by a partial pressure gradient. This is not so. Volatile anaesthetics are believed by almost all to equilibrate rapidly and virtually fully, between alveolar gas and alveolar capillary blood, and . . . [Full Text of this Article]


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