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Continuing Education in Anaesthesia, Critical Care & Pain 2008 8(2):77-79; doi:10.1093/bjaceaccp/mkn008
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© The Board of Management and Trustees of the British Journal of Anaesthesia [2008]. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Multiple Choice Questions

The first 10% of the full text of this article appears below.


   Serotonin and anaesthesia
 

1. Serotonin (5-HT):
  1. Is produced from tryptophan.
  2. Is found in platelets and mast cells.
  3. Has only 3 receptor subtypes.
  4. Acts at both the chemoreceptor trigger zone and the vomiting centre.
  5. Is devoid of effect on the heart.

2. Selective Serotonin-Reuptake Inhibitors (SSRIs):
  1. The mechanism of serotonin syndrome is overstimulation of central 5-HT receptors.
  2. Must always be stopped in the perioperative period.
  3. Are safe in combination with high doses of tricyclic antidepressants.
  4. Hyperreflexia and clonus are manifestations of CNS toxicity.
  5. Neuroleptic malignant syndrome is a consequence of overdose.

3. 5-HT receptor agonists and antagonists:
  1. 5-HT3 antagonists must always be given as sole agents for PONV.
  2. Triptans are 5-HT1 receptor agonists.
  3. Triptans are indicated for the prodromal phase of migraine.
  4. 5-HT4 agonism has anti-anginal utility.
  5. Ketanserin is a 5-HT2 receptor antagonist.

4. In pre-eclampsia:
  1. . . . [Full Text of this Article]


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   Sedation in the intensive care unit
 

   Analgesia for primary hip and knee arthroplasty: the role of regional anaesthesia
 

   Cardiac troponins: their use and relevance in anaesthesia and critical care medicine
 

   Long QT syndrome
 

   Fetal surgery and anaesthetic implications
 

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