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Continuing Education in Anaesthesia, Critical Care & Pain Advance Access originally published online on August 30, 2009
Continuing Education in Anaesthesia, Critical Care & Pain 2009 9(5):152-156; doi:10.1093/bjaceaccp/mkp028
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© The Author [2009]. Published by Oxford University Press on behalf of the British Journal of Anaesthesia. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournal.org

Acute lung injury and acute respiratory distress syndrome

A Mackay, MB ChB FRCA
Specialist Registrar in Anaesthesia and Intensive Care Medicine
Glasgow Royal Infirmary
84 Castle Street
Glasgow G4 0SF
UK

M Al-Haddad, MB ChB FRCA EDIC
Consultant in Anaesthesia and Intensive Care Medicine
Western Infirmary
Dumbarton Rd
Glasgow G11 6NT
UK
Tel: +44 141 211 2291
Fax: +44 141 211 1966
E-mail: malhaddad@doctors.org.uk (for correspondence)

The first 150 words of the full text of this article appear below.


Key points

Acute lung injury (ALI) is a common condition that is associated with a high mortality.
Correct diagnosis of ALI is important because other causes of hypoxaemia may be more easily treated.
Identification and treatment of the underlying condition is paramount.
Management includes standard ICU supportive care and a tidal volume limited to 6 ml kg–1.
A conservative fluid management strategy might have some benefits.

 

Acute lung injury (ALI) is a common condition that is characterized by acute severe hypoxia that is not due to left atrial hypertension. The term ALI encompasses a continuum of clinical and radiographic changes that affect the lungs with the acute respiratory distress syndrome (ARDS) representing the more severe end of this continuum. Despite advances in our understanding of the pathophysiology and management of ALI, it is still associated with a high mortality.

The aim of this review is to provide an overview . . . [Full Text of this Article]


   Definition and diagnosis
 

   Epidemiology
 

   Aetiology
 

   Pathophysiology
 

   Investigations
 

   Management
 
General care

Mechanical ventilation

Fluid management

Steroids

Prone positioning

Other therapies

Nitric oxide

Extracorporeal lung support

Physiotherapy and positioning


   Outcome
 

   Conclusion
 

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