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Continuing Education in Anaesthesia, Critical Care & Pain 2005 5(2):52-55; doi:10.1093/bjaceaccp/mki013
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Continuing Education in Anaesthesia, Critical Care & Pain | Volume 5 Number 2 2005 © The Board of Management and Trustees of the British Journal of Anaesthesia [2005]. All rights reserved. For Permissions, please email: journals.permissions{at}oupjournals.org

Acute lung injury: options to improve oxygenation

Ravi P Mahajan, Reader and Honorary Consultant
University Department of Anaesthesia and Intensive Care, University of Nottingham, Queen's Medical Centre, Nottingham, NG7 2UH
Tel: 01159 709 229, Fax: 01159 700 739, E-mail: ravi.mahajan{at}nottingham.ac.uk (for correspondence)

Persistent hypoxia, despite adequate oxygen therapy, is common in patients suffering from acute lung injury (ALI) or acute respiratory distress syndrome (ARDS). Before attempting advanced support for ALI/ARDS, one must look for and treat relatively readily reversible conditions. These conditions include:

  1. pneumothorax,
  2. pleural effusions,
  3. mucus plugs and retained chest secretions,
  4. major collapse of the lung tissue,
  5. bronchospasm,
  6. cardiogenic pulmonary oedema,
  7. hypotension and low cardiac output, and
  8. equipment failure.
This brief review will address the aetiology, pathophysiology and management options of ALI/ARDS in intensive care.


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