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Continuing Education in Anaesthesia, Critical Care & Pain Advance Access originally published online on August 22, 2005
Continuing Education in Anaesthesia, Critical Care & Pain 2005 5(5):145-148; doi:10.1093/bjaceaccp/mki039
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Continuing Education in Anaesthesia, Critical Care & Pain | Volume 5 Number 5 2005 © The Board of Management and Trustees of the British Journal of Anaesthesia [2005]. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org

Nitrous oxide

Amelia Banks, MBBS BSc MRCP FRCA, Specialist Registrar in Anaesthesia
Department of Anaesthesia, University Hospital, Nottingham, NG7 2UH

Jonathan G Hardman, BMedSci BM BS DM FANZCA FRCA, Senior Lecturer in Anaesthesia
Department of Anaesthesia and Intensive Care, Queen's Medical Centre, Nottingham, NG7 2UH
Tel: 01159 709229, Fax: 01159 700739, E-mail: j.hardman{at}nottingham.ac.uk (for correspondence)

Joseph Priestley, a chemist and Presbyterian minister, discovered nitrous oxide in 1772.1 Its analgesic action was subsequently described in 1800 by Humphrey Davy. Towards the end of the nineteenth century, its anaesthetic properties were recorded under hyperbaric conditions by Paul Bert. Applications for the use of nitrous oxide have developed greatly since that time. It has widespread use in anaesthesia but has many other uses; examples include its use as an aerosol propellant in whipped cream dispensers and for enhancement of engine performance in drag-racing.


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