Continuing Education in Anaesthesia, Critical Care & Pain | Volume 6 Number 2 2006 © The Board of Management and Trustees of the British Journal of Anaesthesia [2006]. All rights reserved. For Permissions, please email: journals.permissions@oxfordjournals.org
Multiple Choice Questions
| The first 150 words of the full text of this article appear below. |
- 1. Regarding general anaesthetic activity:
- The activity of general anaesthetics can be easily deduced from their chemical structure.
- Unitary theories of general anaesthetic action dominate the current literature.
- Most general anaesthetics display a high oil:water partition coefficient.
- Neuronal cell membranes are composed of a homogenous mixture of lipid and protein.
- Some general anaesthetics display stereoselective activity.
- 2. On possible targets of general anaesthetics:
- Transmitter-gated ion channels are the only targets for general anaesthetic agents.
- Transmitter-gated ion channels mediate the majority of fast excitatory and inhibitory neurotransmission within the CNS.
- 5-HT3 and nicotinic acetylcholine (nAch) receptors usually inhibit the activity of CNS neurones.
- GABAA and strychnine-sensitive glycine receptors inhibit the activity of CNS neurones.
- GABAB receptors are considered important targets for general anaesthetics.
- 3. Concerning GABAA receptors:
- GABA is synthesized after the enzymatic conversion of the excitatory amino acid glutamate.
- GABAA receptors are composed of five subunits concentrically arranged around an
. . . [Full Text of this Article]
- The activity of general anaesthetics can be easily deduced from their chemical structure.